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Treatment of Gallstones in Adults Revised 2001
RECOMMENDATION 1: Asymptomatic
gallstones
Surgical consultation and surgery are not recommended for adults who have
asymptomatic gallstones
found incidentally by diagnostic imaging or abdominal surgery.
RECCOMENDATION 2: Symptomatic gallstones
a) Surgical Intervention
If a patient with symptomatic gallstones puts a
relatively high value on preventing recurrent pain
then surgical removal of the gallbladder may be considered. About 70 per cent
of patients will
experience the recurrence of gallstone-related pain if left surgically
untreated. Laparoscopic cholecystectomy
is recommended in symptomatic patients who are suitable candidates for surgery
and
who wish to have surgical intervention.
b) Non-surgical Management
(i) Oral bile acids are rarely indicated for dissolution therapy in patients
who are unsuitable for or
who decline surgery.
(ii) Lithotripsy is not indicated for the primary treatment of simple gallstone
disease.
Most gallstones are asymptomatic and remain so for the life of the
patient.Complications or symptoms
will develop in one to two per cent of patients per year. It also appears that
the longer the stones remain
quiescent, the less likely are complications to appear. Surgery is not
indicated in asymptomatic
patients.Some exceptions include patients with sickle cell disease and
gallstones, and patients with
calcified (porcelain) gallbladders where the risk of gallbladder cancer is
very high. Prophylactic
cholecystectomy had previously been recommended in diabetic patients in order
to avoid the high morbidity and mortality rates associated with emergency
operations. However, the increased risks are
due to cardiovascular disease and other comorbid conditions which are present
whether the surgery
is elective or emergency. Therefore, asymptomatic patients with diabetes should
not have
prophylactic surgery.
Laparoscopic cholecystectomy is now the standard approach to the treatment of
symptomatic gallstones.
A 28-year-old woman with
borderline personality disorder has been stable on fluoxetine and lithium
carbonate for the past year and is adherent with psychotherapy. She now wishes
to become pregnant. Which of the following actions by her psychiatrist is most
appropriate?
a. Continue fluoxetine but discontinue lithium until after the first trimester.
b. Discontinue both lithium and fluoxetine.
c. Maintain both lithium and fluoxetine at current doses.
d. Review risks and benefits of possible treatment options with the patient.
e. Tell the patient that pregnancy is too risky at this point in her treatment.
D
Antidepressants, anticonvulsants, and short-term use of neuroleptics are common for BPD. Decisions about medication use should be made cooperatively between the individual and the psychiatrist. Issues to be considered include the person's willingness to take the medication as prescribed, and the possible benefits, risks, and side effects of the medication, particularly the risk of overdose.
A patient sees a psychiatrist for
frequent shifts in mood and difficulties in interpersonal relationships. After
a complete evaluation, a diagnosis of borderline
personality disorder is made and the psychiatrist discusses a plan of treatment
with the patient. The psychiatrist recommends extended outpatient psychotherapy,but the patient is concerned about the costs of care. Which
of the following responses by the psychiatrist is most appropriate?
a. If cost is an issue, meeting intermittently for therapy will be less
expensive even if occasional hospitalizations are needed.
b. Surprisingly, this kind of therapy is cheaper than being seen for medication
management alone.
c. There is good evidence that this kind of therapy is often effective for your
disorder; briefer treatment may not work.
d. This kind of therapy is prohibitively expensive, but your insurance plan
should cover most of the cost.
Answer is C. A combination of
psychotherapy and medication appears to provide the best results for treatment
of BPD. Medications can be useful in reducing anxiety, depression, and
disruptive impulses. Relief of such symptoms may help the individual deal with harmful
patterns of thinking and interacting that disrupt daily activities.
However, medications do not correct ingrained character difficulties. Long-term
outpatient psychotherapy and group therapy (if the individual is carefully
matched to the group) can be helpful.
DSM-IV-TR incorporated changes
from DSM-IV in diagnostic criteria for the following:
Tourette's Disorder
Dementia of the Alzheimer's Type; Dementia Due to Other General Medical
Conditions
Personality Change Due to a General Medical Condition
Exhibitionism; Frotteurism; Pedophilia; Sexual Sadism; Voyeurism
When a sexually-transmitted
disease (STD) is suspected as a possible cause of symptoms associated with UTI,
a good antibiotic choice is
a. A fluoroquinolone antibiotic because they are effective
treatment for coliform bacteria, gonococci, and Chlamydia.
b. TMP/SMX because it is effective treatment for coliform bacteria.
c. Doxycycline because it is an effective treatment for Chlamydia, which is a
very common cause of STD.
d. Ampicillin plus gentamicin to ensure clinical cure.
Answer is A. Quinolones make sense, because we know they are very effective at treating the UTI. And also, at least most of the quinolones that we use, Cipro is not that great against Chlamydia, but the other ones that we're generally using will basically treat all of these.
Which of the following diagnostic
tests should be given to a patient who presents for the first time with
dysphagia?
a. Barium esophagram
b. Histologic staining
c. 24-hour esophageal pH monitoring
d. None of the above
Answer is A. Use barium esophagram
only in those patients who present for the first time with dysphagia. It helps
us to give further information about the cause of their dysphagia. It serves as
a road map before the gastroenterologist decides what kind of procedure to
embark on.
Endoscopy should be indicated in patients who present for the first time with
alarm symptoms, for example, dysphagia, odynophagia, anorexia, or weight loss.
These are all ominous symptoms that may suggest that there is a mechanical
obstruction, and there might be a lesion in the esophagus that needs to be
further addressed. Also, we should consider endoscopy when we would like to
exclude Barrett's esophagus.
When we should do endoscopy in these patients is unclear and remains an area of
intense controversy. But recent American College of Gastroenterology practice
guidelines suggest that patients who had symptoms of heartburn and acid
regurgitation for at least 5 years should be endoscoped at least once to
exclude Barrett's esophagus.
Twenty-four hour esophageal pH monitoring should be considered in patients who
failed standard-dose PPI treatment. I would consider doing it on medication
only to see if the PPI suppressed their acid properly.
In addition, some of the patients who have no documentation of EE prior to
antireflux surgery should have a 24-hour esophageal pH monitoring done to
demonstrate abnormal acid exposure.
Which of the following is NOT a
contraindication to PTCA?
a. Left main disease
b. Presence of a single lesion
c. Chronic occlusions
d. Diabetes
B
Indications for PTCA have not changed significantly since its inception. Success and complication rates, however, have significantly improved. The method is still best applied to single vessel disease.
Which of the following is
standard-of-care for acute asthma?
a. Aerosolized corticosteroids
b. Intravenous corticosteroids
c. Aerosolized beta-agonists
d. Oral beta-agonists
Answer is C. Aerosolized beta-agonists are now standard-of-care for acute asthma. Approximately two thirds of patients with acute asthma respond to treatment with nebulized albuterol sufficiently for discharge from the hospital.
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